The Twinkly integration allows you to control Twinkly LED string from Home Assistant.
The Twinkly devices does not store the effects locally, they are instead re-sent from the Twinkly application each time. This means that this integration does not support to change the LED string effect. It only supports to configure the brightness and to turn the device on and off.
You can setup this integration from the Home Assistant user interface:
In Home Assistant, go to Configuration > Integrations.
At the bottom right, click on the + button.
In the list select the Twinkly integration.
Configure the host (or IP address) of your twinkly device.
If configured using an IP address, on your router / DHCP, you should assign a static IP to your Twinkly device.